Istamet 50mg/500mg Tablet: View Uses, Side Effects, Price and Substitutes | 1mg (2024)

Q. Is it safe to take alcohol while I am taking Istamet 50mg/500mg Tablet?

No, it is not safe to alcohol along with Istamet 50mg/500mg Tablet, as it can increase the chances of lactic acidosis.

Q. What are the instructions for storage and disposal of Istamet 50mg/500mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Can the use of Istamet 50mg/500mg Tablet lead to lactic acidosis?

Yes, the use of Istamet 50mg/500mg Tablet can lead to lactic acidosis. It is a medical emergency which is caused by the increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Sitagliptin + Metformin and immediately consult your doctor.

Q. What is Istamet 50mg/500mg Tablet?

Istamet 50mg/500mg Tablet is a combination of two medicines: Sitagliptin and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus. It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. Sitagliptin inhibits the enzyme DPP4 and increases the release of insulin from the pancreas. This combination is not indicated for the patients below 18 years of age.

Q. What are the possible side effects of Istamet 50mg/500mg Tablet?

The use of Istamet 50mg/500mg Tablet is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effect like lactic acidosis. On long-term use it can also lead to Vitamin B12 deficiency.

Q. Are there any specific conditions in which Istamet 50mg/500mg Tablet should not to be taken?

The use of Istamet 50mg/500mg Tablet should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine should be avoided in patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis.

Q. Is it safe to take alcohol while I am taking Istamet 50mg/500mg Tablet?

No, it is not safe to alcohol along with Istamet 50mg/500mg Tablet, as it can increase the chances of lactic acidosis.

Q. Can the use of Istamet 50mg/500mg Tablet lead to lactic acidosis?

Yes, the use of Istamet 50mg/500mg Tablet can lead to lactic acidosis. It is a medical emergency which is caused by the increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Sitagliptin + Metformin and immediately consult your doctor.

Q. Can the use of Istamet 50mg/500mg Tablet lead to Vitamin B12 deficiency?

Yes, the use of Istamet 50mg/500mg Tablet can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems as a result of which the patient can feel tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.

Q. What are the instructions for storage and disposal of Istamet 50mg/500mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. What is Istamet 50mg/500mg Tablet?

Istamet 50mg/500mg Tablet is a combination of two medicines: Sitagliptin and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus. It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. Sitagliptin inhibits the enzyme DPP4 and increases the release of insulin from the pancreas. This combination is not indicated for the patients below 18 years of age.

Q. What are the possible side effects of Istamet 50mg/500mg Tablet?

The use of Istamet 50mg/500mg Tablet is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effect like lactic acidosis. On long-term use it can also lead to Vitamin B12 deficiency.

Q. Are there any specific conditions in which Istamet 50mg/500mg Tablet should not to be taken?

The use of Istamet 50mg/500mg Tablet should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine should be avoided in patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis.

Q. Is it safe to take alcohol while I am taking Istamet 50mg/500mg Tablet?

No, it is not safe to alcohol along with Istamet 50mg/500mg Tablet, as it can increase the chances of lactic acidosis.

Q. Can the use of Istamet 50mg/500mg Tablet lead to lactic acidosis?

Yes, the use of Istamet 50mg/500mg Tablet can lead to lactic acidosis. It is a medical emergency which is caused by the increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Sitagliptin + Metformin and immediately consult your doctor.

Q. Can the use of Istamet 50mg/500mg Tablet lead to Vitamin B12 deficiency?

Yes, the use of Istamet 50mg/500mg Tablet can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems as a result of which the patient can feel tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.

Q. What are the instructions for storage and disposal of Istamet 50mg/500mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Istamet 50mg/500mg Tablet: View Uses, Side Effects, Price and Substitutes | 1mg (2024)

FAQs

What is the price of Istamet 50 500 box? ›

Sitagliptin And Metformin Istamet 50 MG 500 MG, Packaging: 2 X 15 Tablet, Box at Rs 810.62/box in Ahmedabad.

What is the generic name for istamet? ›

Sitagliptin advertised as the phosphate salt under the exchange name Istamet, Januvia, is an oral antihyperglycemic (antidiabetic sedate) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class.

Are Metformin and istamet the same? ›

A: The composition of both these medications is the same—a combination of sitagliptin and metformin; however, the brand names are different. You should only take the medicine prescribed by your doctor, as the same will be based on your medical history and the severity of your condition.

What are the benefits of taking Istamet? ›

Istamet D -XR 1000 Tablet is a combination medicine that helps control blood sugar levels. This medicine is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It helps in proper utilization of insulin, thereby lowering the blood sugar level.

What is the price of JANUMET 50 1000 in the US? ›

Janumet (metformin/sitagliptin) is a member of the antidiabetic combinations drug class and is commonly used for Diabetes - Type 2. The cost for Janumet (1000 mg-50 mg) oral tablet is around $613 for a supply of 60 tablets, depending on the pharmacy you visit.

Is there a generic for JANUMET 50 500? ›

Janumet and Janumet XR contain the active ingredients sitagliptin and metformin. Janumet and Janumet XR are available only as brand-name medications. They're not currently available in generic form. Sitagliptin and metformin are available separately as generic medications.

Is istamet safe for kidneys? ›

The use of Istamet 50mg/500mg Tablet should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine should be avoided in patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis.

When is the best time to take istamet? ›

Istamet 50 mg/500 mg Tablet should be taken with food to avoid an upset stomach. Istamet 50 mg/500 mg Tablet should be taken at the same time of the day each time for best results. For better advice, your doctor will decide what dose should be taken, and it can change in time depending on your condition.

Is sitagliptin better than metformin? ›

No statistically significant differences were found between treatment groups. Therapeutic effect of sitagliptin was observed in patients with PCOS comparable to metformin and the combination of metformin-sitagliptin is more effective in terms of ovulation than the other two treatments alone.

Which is better Janumet or metformin? ›

JANUMET can help lower blood sugar more than metformin alone. People who added sitagliptin saw an additional drop in their A1C number: Sitagliptin lowered A1C an average of 0.7%, from 8% at start. Placebo lowered A1C an average of 0%, from 8% at start.

Which company makes Istamet? ›

Istamet (500/50 mg) Tablet is a combination medicine used for the treatment of type 2 diabetes mellitus. Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect.

What does 50 500 istamet contain? ›

Istamet (500/50 mg) Tablet is a combination of Metformin and Sitagliptin. Metformin works by increasing the action of insulin (a hormone that keeps the blood sugar at an appropriate level) in the body, decreasing the absorption of sugar from the intestine, and decreasing the production of sugar in the liver.

What are the side effects of istamet XR 500mg? ›

The most common side effects of Istamet Xr Tablet are low blood sugar levels, stomach upset, constipation, diarrhoea, a metallic taste in the mouth, sore throat, stuffy nose, and joint pain. Talk to your doctor if these side effects bother you.

Who should not use sitagliptin? ›

have ever had an allergic reaction to sitagliptin or any other medicine. have problems with your pancreas. have gallstones or very high levels of triglycerides (a type of fat) in your blood. are a heavy drinker or dependent on alcohol.

What is the main side effect of sitagliptin? ›

The most common side effect of sitagliptin, which happens in more than 1 in 100 people, is headaches. Talk to your doctor if headaches last longer than a week or are severe. If taking sitagliptin gives you a headache, make sure you rest and drink plenty of fluids.

What is the price of dapagliflozin sitagliptin combination brand? ›

Dapagliflozin (10mg) + Sitagliptin (100mg) Tablet, Packaging Size: 10X10 at Rs 528/box in Nashik.

What is the price of sitagliptin and metformin? ›

Product Summary
Offer Price₹330.00
You Save₹45.00 (12% on MRP)
ContainsMetformin Hydrochloride(500.0 Mg) + Sitagliptin(50.0 Mg)
UsesType 2 Diabetes mellitus
Side effectsNausea, runny nose, headache, sore throat, flatulence
1 more row
Mar 20, 2024

How much is a 30 day supply of sitagliptin? ›

Januvia (sitagliptin) is a member of the dipeptidyl peptidase 4 inhibitors drug class and is commonly used for Diabetes - Type 2. The cost for Januvia ((as phosphate) 100 mg) oral tablet is around $613 for a supply of 30 tablets, depending on the pharmacy you visit.

What is the market price of sitagliptin phosphate? ›

Notably, the maximum retail price for a pack of ten Sitagliptin phosphate tablets 50 mg is ₹60, while the same for Sitagliptin phosphate tablet 100 mg is ₹100.

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